**Question 119**
**Specialty: Gastroenterology**
**Paraphrased Question:**
A 55-year-old man with a history of chronic Hepatitis C presents with a right upper quadrant mass. Imaging studies reveal a 6 x 6 cm mass consistent with hepatocellular carcinoma. What is the best management approach for this patient?
**Options:**
A) Chemotherapy
B) Radiotherapy
C) Transcatheter arterial chemoembolization (TACE)
D) Surgical resection
E) Liver transplantation
**Correct Answer:**
C) Transcatheter arterial chemoembolization (TACE)
**Explanation:**
TACE is considered the standard of care for intermediate-stage hepatocellular carcinoma (HCC) in patients who are not candidates for surgery. This method allows targeted delivery of chemotherapy directly to the tumor while reducing systemic exposure, making it an effective treatment option for managing this condition. Surgical resection may be an option for early-stage HCC, but in this scenario with a 6 x 6 cm mass, TACE is more appropriate.